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Finally, NAC supports the Nrf2-dependent transcription pathway, a genetic cellular defense mechanism that upregulates the production of endogenous antioxidant enzymes, providing a robust buffer against the oxidative damage to DNA, proteins, and lipids that naturally occurs with aging and chronic illness

Thus, FOXO4-DRI is able to recognise and target the problem cells without damaging the healthy ones

Slominski AT, Kim TK, Janjetovic Z, Slominski RM, Ganguli-Indra G, Athar M et al (2025) Melatonin and the skin: current progress and perspectives for human health

The mixture was then diluted in 0.5 ml of 1:10 g methanol: water