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We revealed that both drugs occupied a bifurcated binding pocket divided by a conserved salt bridge between E124 3.33 and R283 6.55
When to seek urgent medical attention : Severe, persistent abdominal pain that does not resolve (if pancreatitis is suspected, stop taking the medication and seek immediate medical assessment) Signs of dehydration from persistent vomiting or diarrhoea (which can lead to acute kidney injury) Allergic reactions (rash, difficulty breathing, swelling of face or throat) Symptoms of hypoglycaemia if taking other glucose-lowering medications (shakiness, confusion, sweating) Regular follow-up with your healthcare team is essential to monitor your response to treatment, adjust doses appropriately, and address any concerns promptly
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Presented for research literature review only Jiang W et al
"But obesity is a chronic, complex disease, so it may not be an either-or situation, as some people may benefit from a combined approach," says Dr
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