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The incretin hormone receptors (GIPR and GLP-1R) are widely distributed beyond the pancreas, principally in the brain, cardiovascular and immune systems, gut and kidney, consistent with a broad array of extrapancreatic incretin actions
These drugs also appear to reduce microglial activation (neuroinflammation) and enhance neuroplasticity
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Effect of glutamine on oxidative stress, inflammatory, and glycation markers, and the activity of glyoxalase system in diabetic rats with atherosclerosis
Moreover, epinephrine constricts our blood vessels, dilates our lungs, and speeds up our respiration rate to prepare our body for mobilization in response to stress [ 8 , 11 ]
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