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Ethics declarations Ethics statement This was a review study
The first reported change is usually deeper, more consistent sleep
4 How Mounjaro works Mounjaro activates two hormone receptors instead of one: Like Rybelsus, it activates the GLP-1 receptor It also activates GIP (glucose-dependent insulinotropic polypeptide), a second gut hormone involved in appetite regulation and blood sugar control This dual-action mechanism likely explains why tirzepatide produces greater weight loss and improvements in blood sugar in clinical trials than GLP-1-only medications
However, hurdles to their widespread use, such as manufacturing cost, delivery system, and side effects remain, especially in low- and middle-income countries
Kryukov, G
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