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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are novel drugs approved for diabetes and obesity

1,2 For the co-primary endpoints, retatrutide lowered weight by up to an average of 28.7% (71.2 lbs) and reduced pain by up to an average of 4.5 points (75.8%) using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score

Although retatrutide has shown substantial weight-loss efficacy in adults with obesity, the relative contributions of reduced appetite, altered food reward, enhanced energy expenditure, and glucagon-related metabolic effects remain incompletely understood (109)

Follow your provider instructions or the medication guide exactly

At the low end, a consensus of analysts surveyed by Bloomberg News expects Foundayo peak sales to reach $18 billion by 2030