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Synergistic Effect The combination of GLP-1, GIP, and glucagon activation produces a more potent impact than each individual hormone alone

MOTS-C directly addresses this by optimizing mitochondrial ATP production

19 The researchers looked at records of over 3.8 million patients who had type 2 diabetes to assess the time to development of NAION after initiation of GLP-1 treatment

[45] Cardiovascular conditions such as hypertension, congestive heart failure, or recent myocardial infarction may represent relative contraindications due to prednisones potential effects on fluid retention and electrolyte balance