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In addition, sorbitol dehydrogenase in granulosa cells reduces glucose to form sorbitol, which is then fed by oocytes indirect fructose synthesis (40)
Vukojevic et al., 2020)
More recently, spinocerebellar ataxia type 2 has also been linked to the presence of a transition polymorphism in the GSTO2 gene (rs2297235 A183G) which significantly correlates with the age at disease onset
Lipoic acid has been found to activate the insulin signaling cascade in cultured cells (3, 42, 43), increase GLUT4 translocation to cell membranes, and increase glucose uptake in cultured adipose and muscle cells (44, 45)
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