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Some studies have demonstrated the ability of gut-derived GLP-1 to cross through the blood-brain barrier and thoroughly perfuse the brain parenchyma, but whether its effects are similar to that of PPG-derived GLP-1 remains to be established [50, 53]
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Clinically, semaglutide did not slow cognitive decline to a statistically meaningful degree compared with placebo
BMC Gastroenterol 17:96 Kovacs-Nolan J, Rupa P, Matsui T, Tanaka M, Konishi T, Sauchi Y, Sato K, Ono S, Mine Y (2014) In vitro and ex vivo uptake of glutathione (GSH) across the intestinal epithelium and fate of oral GSH after in vivo supplementation
P.ZhangW.BansbackN.AmarsiZ.BirminghamC
![PDF] Methylene blue and its importance in medicine](https://figures.semanticscholar.org/61e65ce61147269207eefbe85e59f24c41f25ac3/3-Figure2-1.png)
