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All significance (Sig.) values were 2-tailed

On average, people who took the treatment lost 14.9% of their body weight from baseline to week 68, while those who took a placebo lost only 2.4% of their body weight

This is normal and doesn't mean you should stop taking the medication

Moreover, it has an in vitro pharmacological profile that mimics the signaling of native GIP at the GIPR, but it is biased at the GLP-1R to favor cyclic AMP (cAMP) generation over -arrestin recruitment 16