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The dulaglutide (Trulicity) shortage was resolved in June 2025
It is the first GLP-1 receptor agonist tablet for weight-loss to be approved by the Medicines and Healthcare products Regulatory Agency (MHRA), making the UK the third country to authorise the pills, behind the US and the United Arab Emirates
In order to keep weight off, people need to continue taking the GLP-1 medications indefinitely
The underlying pathophysiology is mostly unresolved, with immunological factors often, but not exclusively, occurring after an initial infection with a distinct or gradual onset
THC may affect appetite for some people, but responses vary
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