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This is significant because the approved versions of these medications explicitly state "Do not freeze and do not use if it has been frozen." Freezing can damage peptide structures, potentially reducing potency or altering the compound in ways that affect both efficacy and safety

caution is warranted

If you are taking GLP-1 medications, make a conscious effort to drink water throughout the day, even when you do not feel thirsty

10.1016/j.freeradbiomed.2017.08.006 316 SpitzD

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