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By avoiding the growth hormone receptor/IGF-1 pathway entirely, AOD-9604 eliminates the appetite-modulating effects that make growth hormone therapy challenging for weight management

Notably, SLC38A9 is necessary for not only leucine but also other essential amino acids (e.g., glutamine, tyrosine, and phenylalanine) that are generated via lysosomal proteolysis and efflux from lysosomes in an arginine-stimulated fashion to activate mTORC1 (Rebsamen et al., 2015

However, as with any biological therapy, the theoretical possibility of individual hypersensitivity cannot be entirely eliminated, and appropriate monitoring remains prudent

Stimulates the formation of new blood vessels