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doi: 10.4049/jimmunol.0900948 147 BinderCJHorkkoSDewanAChangMKKieuEPGoodyearCSet al
The broader clinical data is encouraging
The return of hunger hormones like ghrelin and the resumption of pre-treatment appetite signals explain why short-term treatment alone rarely produces lasting results without sustained behavioral change
Current expectations point to FDA review and potential approval in the 2027 to 2028 range
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