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The SURPASS-J-combo trial embraced diabetic adults with HbA 1c 7% to 11% and BMI 23 kg/m 2 , stable weight and uncontrolled with therapy of metformin, thiazolidinedione, sulfonylureas, meglitinide, alpha-glucosidase inhibitor or SGLT2-i (81)
For reference: FDA-approved Vyleesi uses single dose of 1.75 mg
Blood glucose levels can begin to rise within days to weeks after stopping, depending on individual metabolic factors and the presence of other diabetes medications
Staying within the broader abdominal zone but well clear of the navel gives you a large, consistent target area with good medication uptake
Injection Technique Subcutaneous injection guidance from clinical best-practice resources [9] [11]
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