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Diabetes, Obesity and Metabolism 25 (9)
Extracellular Matrix Expression and Production in Fibroblast-Collagen Gels: Towards an In Vitro Model for Ligament Wound Healing
The most studied mechanisms include: upregulation of growth hormone receptors in fibroblasts (increasing sensitivity to healing signals), activation of the FAK-paxillin pathway (promoting cell adhesion and migration), modulation of the nitric oxide system through Src-Caveolin-1-eNOS phosphorylation (enhancing vascular function), and dual activation of the Egr-1/NAB2 gene loop (promoting organized, non-chaotic blood vessel growth)
Because it acts at the cellular level rather than on appetite or hormones, interest in it extends beyond weight loss into longevity and metabolic disease prevention
Good options: Protein shake with banana Grilled chicken breast Salmon with vegetables Cottage cheese with fruit Before Bed 20-30g slow-digesting protein (like casein or Greek yogurt) supports overnight muscle protein synthesis
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