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Rapid weight loss can stress joints, connective tissue, and muscle

The 6-year follow-up study showed no increased incidence of neoplasia, autoimmune events, or endocrine disruption

Unlike oral B12 supplements, which depend on intrinsic factor production in the stomach for absorption and lose 5070% bioavailability in the digestive process, injectable B12 achieves near-100% bioavailability by delivering the vitamin directly into circulation

Nevertheless, as early as the 1950s, there were studies suggesting that oral vitamin B12 replacement may provide adequate absorption

The optimal choice depends on the nature of the condition, treatment goals, and individual response patterns