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If experiencing symptoms such as sweating, tremor, palpitations, confusion, or dizziness, patients should check their blood glucose as these may indicate hypoglycaemia, particularly in those taking concomitant insulin or sulphonylureas

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Under normal conditions in senescent cells, FOXO4 interacts with p53 and retains it in the nucleus, preventing p53 from translocating to mitochondria and executing its intrinsic pro-apoptotic programme