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DNA is particularly vulnerable, as oxidative lesions such as eight-oxoguanine accumulate, leading to replication errors and genomic instability
Ongoing investigations commonly focus on tissue regeneration, connective tissue biology, cellular repair pathways, inflammatory signaling networks, wound healing mechanisms, extracellular matrix research, and regenerative science models
Kuczler, M
Blood 127:801809 Ware RE, de Montalembert M, Tshilolo L, Abboud MR (2017) Sickle cell disease
Research Highlights Wound Healing & Skin Regeneration Promotes angiogenesis, fibroblast activation, and collagen remodeling, accelerating tissue repair in preclinical studies
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