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Gastrointestinal adverse events, mostly mild or moderate, were more frequent in the treatment group (72.5%) than in the placebo group (34.4%)
Your clinician may gradually titrate your dose upward based on your response and goals, but every increase is planned, documented, and medically justified
Jia, T., Carrero, J
Semaglutide 2.4 mg Once Weekly in Adults with Overweight or Obesity: Meta-Analysis
Spironolactone is also not safe in pregnancy because of its anti-androgen effects, so pregnancy avoidance is essential if there is any chance of conception
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