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Swanson JM et al (1999): Acute tolerance to methylphenidate in the treatment of ADHD in children
The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)
Thioredoxin reductases In mammals, three selenocysteine-containing thioredoxin reductase (TXNRD) isoenzymes have been identified in the thioredoxin system: cytosolic TXNRD1, mitochondrial TXNRD3, and testes-specific thioredoxin glutathione reductase (TXNRD3, also known as TGR)
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5 The practical takeaway for you is unchanged: correct any deficiency, but routine high-dose supplementation if you already have sufficient levels has not been shown to add fertility benefit
