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difficile toxins in humans and in preclinical model, and changes to the ENS and extrinsic innervation contribute to intestinal inflammation, damage and secretory diarrhoea

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Nature 2006;444:10271031

[78] da Cunha MSB, Campos Hankins NA, Arruda SF

Consistency matters more than the specific time of day, though some researchers prefer morning injections to manage initial nausea during waking hours when they can eat lightly and stay hydrated