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Next, we introduced multiple mutations in HGF, including point mutations (W321R, E336R, E361R, R373E, and Y376A), double mutation (W321R/Y376A), and triple mutation (W321R/E361R/Y376A), designed to weaken the interface III

SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines

Belcher, J

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Whether and how any of this translates into a meaningful outcome for a specific individual is exactly the kind of question that belongs in a clinical evaluation, not a generalized article