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While individual sensitivity varies, caffeine has a half-life of approximately 5 to 6 hours, meaning half of the caffeine from an afternoon coffee remains in your system at bedtime

What if it comes down to where exactly on the thigh you are placing that needle

then its essential that you stop using the product and (depending on the severity of the situation) either contact your doctor or get emergency medical assistance

(Also see our Top Picks among protein supplements.) Clinical Update 4/29/2018 When to Take Protein When is the best time of day to take a protein supplement if you want to gain muscle but lose fat