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It contains an absorption enhancer (SNAC) that allows the medication to be absorbed through the stomach lining, but requires specific administration instructions including taking it on an empty stomach with limited water and waiting 30 minutes before eating or taking other medications
Gastrointestinal Effects (most common) GI symptoms are the most frequent adverse effects and occur in a dose-dependent manner, typically within 48 hours of initiation or dose escalation
Gul S et al
Verbraucherzentrale NRW, Dsseldorf 2004, ISBN 3-933705-91-6
These conditions may affect L-cell populations and function
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