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Weight loss over the intervention period (median 9.6 years) was 6.0% for calorie restriction and 3.5% for controls
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Additionally, some of the medications prescribed, including GLP-1s, bupropion, and topiramate, come with potential side effects such as nausea, dizziness, and metabolic disturbances, which may require close monitoring
Individuals with the TT genotype may experience subtle differences in how efficiently neurons strengthen connections in response to learning, stress adaptation, or cognitive stimulation
Avoiding greasy, heavy, or excessively spicy food reduces symptoms substantially
