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According to the Phase 3 trial involving around 2,500 patients, people taking the highest dose of Retatrutide lost an average of 28.3 per cent of their body weight, approximately 70 pounds, over 80 weeks

declares additional funding for this work through the UK MRC (grant MR/ K022202)

This effect is more commonly associated with very high protein intakes and is generally mild in the context of a balanced calorie-restricted diet

The medication's effect is most powerful when paired with foods that support satiety and metabolic health

However the sky-high prices of GLP-1 drugs, which can cost over $1,000 a month in the United States, have raised concerns they will not be made available in poorer nations where they could save the most lives