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That being said, some people who have taken injectable vitamin B12 have complained of difficulty walking and balancing, nervousness, anxiety, weakness, lack of coordination, and even a sensation of pins and needles, per SFGate

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Quick answer: In the Phase 2 clinical trial (Jastreboff et al., 2023, New England Journal of Medicine ), retatrutide was given by once-weekly subcutaneous injection across a 112mg range