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People were tested on these weekly doses: 1 milligram (mg) 4 mg (starting at either 2 mg or 4 mg) 8 mg (starting at either 2 mg or 4 mg) 12 mg (starting at 2 mg) The highest dose tested was 12 mg per week , and the gradual increase was important for making side effects easier to handle
It's important to note that these NHS commissioning criteria are more restrictive than the licensed indications, which permit use at lower BMI thresholds
Tirzepatide is part of a new group of drugs called dual incretin receptor agonists
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