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In about 17,600 adults with obesity and established cardiovascular disease but no diabetes, semaglutide cut major cardiovascular events by 20% over roughly 40 months. This is a secondary-prevention result in people who already had heart disease

Abnormal levels of tryptophan can therefore negatively impact immune responses, metabolic stress pathways, and brain function, leading to a wide range of symptoms associated with ME/CFS and FM (Gostner et al., 2020)

LR3 circumvents this, resulting in significantly higher free bioavailability at the receptor

10.3390/brainsci12020132 12 BaraniukJ