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The mechanism is plausible and supported by the original Harding lab work
The type of reaction may also depend on the formulation, route of administration, individual sensitivity and other health factors
Stem Cell Mobilisation, Scar Reduction & Multi-System Repair (PubMed, 2012) A comprehensive review of TB4s biological properties confirmed it is released by platelets, macrophages, and multiple cell types following injury, where it protects tissues from further damage while reducing apoptosis, inflammation, and microbial growth
Why Its Different from Retinoids and Peels Retinoids and chemical peels work by speeding up cell turnover, which can be effective but also quite harsh on the skin
Of course, if this fat is hanging that also indicates loose skin - and for that you can sometimes see a small improvement in skin retraction just by taking away the weight of that fat hanging on it - but you may also need skin tightening or skin removal surgery to achieve your goals
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