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By integrating pharmacological theory with modern signaling pathway analysis within a unified functional classification system, this review provides a scientific foundation for personalized, targeted, and evidence-graded sports nutrition strategies
Wheeler DD
The anti-cancer effects of fucoidan: a review of both in vivo and in vitro investigations
Reichelt KL, Fonnum F
The GLP-1 receptor is a class B G protein-coupled receptor (GPCR) found in: Pancreatic beta cells Hypothalamic and brainstem nuclei Gastrointestinal tract Heart, kidney, and elsewhere Upon activation, it triggers multiple intracellular pathways: cAMP/PKA: enhances insulin secretion PI3K/Akt: promotes cell survival and beta cell function MAPK/ERK: involved in cell proliferation, differentiation, and potentially neuroprotective effects These pathways interact in complex ways depending on cell type, receptor density, and ligand properties
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