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The excess floods the pituitary with GHRH signal, leading to receptor desensitization within days rather than months
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Voet, D
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These asymptomatic hosts could act as reservoirs, enhancing transmission, which underscores the need for vigilant monitoring of AmB-resistant Leishmania martiniquensis , particularly in relapsing and HIV-coinfected patients (Figure 2 highlights how alterations at key enzymatic steps can lead to the production of alternative sterols that diminish AmB efficacy
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