doi: 10.1016/j.cmet.2023.11.009 269 McLeanBAWongCKKaurKDSeeleyRJDruckerDJ
47 Mitchell et al 41 demonstrated through studies that GLP-1R was expressed on human eosinophils and neutrophils and that GLP-1 analogues significantly reduced the expression of eosinophil surface activation markers CD11b and CD69 and decreased eosinophil production of factors such as IL-4, IL-8 and IL-13
Search Strategy Five electronic databases, PubMed, Scopus, Web of Science, ClinicalTrials.gov, and PsycNet, were searched on June 10, 2023, using the search terms (semaglutide OR GLP-1 analog OR GLP-1 agonist) AND (psychiat* OR depress* OR anxiety OR psycho* OR schizo* OR bipolar OR substance OR ADHD OR attention OR dementia OR autism OR alcohol use disorder OR AUD OR Alzheimers disease) AND (treatment). No restrictions on language, country, publication year, or patient age, gender, or ethnicity were applied
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Ultimately, however, coverage varies by policy