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In pediatric patients there was no statistically significant benefit, but in adult patients FEV1 values were significantly improved starting at three months, and the benefit persisted at the six- and nine-month evaluations

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Engelhardt K, Ferguson M, Rosselli JL

The key values taken under consideration were R2 ( gross elasticity of the skin including viscous deformation, ratio of ability of recovery to final distension values) and R6 (portion of visco-elasticity on the elastic part of the curve, the smaller the value the higher the elasticity and the skin barrier firmness)