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Side effects are usually mild and limited to skin sensitivity, irritation, or sun sensitivity

Starting with a lower concentration allows your skin to adjust gradually

The treatment normalized serum corticosterone levels, enhanced central GABA and serotonin concentrations and reduced peripheral inflammation and gut microbiota profiling revealed a reduction in potentially pathogenic genera ( Acinetobacter, Enterococcus, Bacillus ) and increased abundance of beneficial taxa ( Muribaculum, Alistipes, Lactobacillus ), indicating the therapeutic potential of targeted psychobiotic intervention for stress-related disorders (Tyagi et al., 2025)

PMCID: PMC6720777