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Together with other aspects of the PWS phenotype including, in many cases, a reduced sensitivity to pain, hyperphagia results in life-threatening obesity and life-shortening complications for some people with PWS

Angiotensin II Receptor Blockers (ARBs) Mechanism: Block Angiotensin II receptors vasodilation, aldosterone Examples: Losartan, Valsartan, Olmesartan Key Points: Alternative for patients who cannot tolerate ACE inhibitors (e.g., cough) 6

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Number two, I assess skin quality, because rapid weight loss and gradual weight loss leave the skin in very different places

PMCID: PMC11790292