In SUMMIT, tirzepatide reduced the composite of cardiovascular death or worsening heart-failure events by 38% (HR 0.62, 95% CI 0.410.95) and worsening HF events alone by 46% (HR 0.54, 95% CI 0.340.85), with a +6.9-point between-group improvement in the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS), an 18-meter improvement in 6-minute walk distance (6MWD), and a placebo-adjusted weight loss of 11.6% [5]
Think: progress, not panic
Many patients prescribed Wegovy (semaglutide 2.4 mg) for weight management wonder what is the best time of day to take Wegovy to maximise results
But I do think [this memo] signals a frontal attack on basic tenets of the disability rights movement, said Jennifer Lav, director of the Disability Practice Area at the National Health Law Program
Some practitioners prefer twice-daily dosing of 125-250 mcg to maintain stable blood levels throughout the day