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The STEP trials showed continued weight loss improvement at higher doses, with the dose-response relationship remaining positive through 2.4 mg
Myeloproliferative neoplasms (such as polycythaemia vera or chronic myeloid leukaemia) and acute leukaemias can increase B12-binding proteins (transcobalamins), raising total serum B12
Shao J, Fujiwara T, Kadowaki Y, et al
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It is often accompanied by chronic fatigue, muscle loss, osteoporosis, depressive states or increased risk of cardiometabolic disorders
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