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J Comp Neurol 226:403420

Constitutive activation of NRF2 has been considered as a resistance mechanism to chemo or radiation therapy because the NRF2-mediated antioxidant response eliminates therapy-induced ROS, thereby promoting cell survival

For example, GshB has two protein clusters associated with it (PRK12458 and PRK05246), so if the first hit from RPS-Blast for a protein was any one of these clusters, the protein was assumed to be GshB

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Therefore, monitoring of the platelet count and serum potassium concentrations are recommended during therapy