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76,77 In summary, disc cells respond to altered loads and osmotic pressures, to DAMPs, MMPs and pro-inflammatory cytokines with the expression of catabolic enzymes, with anabolic healing attempts, and with inflammation resulting in failed healing attempts, damage accumulation and chronic inflammation leading eventually to DD
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Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, et al
Nonapeptide Neuromodulatory nonapeptide for sleep architecture research DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino acid neuropeptide first isolated from cerebral venous blood
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