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Busetto L, Dicker D, Azran C, et al
Cells were plated in a 96-well plate at a density of 50,000 cells per well and were cultured for 2448 h
These modifications extend the drugs half-life, enabling weekly dosing [19]
Signs of a serious allergic reaction include difficulty breathing, swelling of the face, lips, tongue, or throat, severe rash or hives, rapid heartbeat, and severe dizziness or fainting
Red flags requiring immediate evaluation include severe abdominal pain (possible pancreatitis), persistent vomiting leading to dehydration, suicidal thoughts, development of new eating disorder behaviors, syncope, chest pain, hematemesis/melena, severe constipation/obstipation, orthostatic hypotension, or marked electrolyte abnormalities
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