Weight loss with GLP-1s comes with a cascade of benefits: blood sugar normalizes, blood pressure drops, and cholesterol improves
Contrave is contraindicated in patients with uncontrolled high blood pressure, a seizure disorder or history of seizures, current use of other bupropion-containing products (such as Wellbutrin), bulimia or anorexia nervosa, chronic opioid use or current use of opioid agonists like methadone or Suboxone, current use of MAO inhibitors, or known allergy to naltrexone, bupropion, or any component of Contrave
*Patients must be physically located in a state where our providers are licensed at the time of prescribing
Always follow the manufacturer's recommended titration schedule in the SmPC, and consider extending the time at lower doses if patients experience significant gastrointestinal symptoms
However, differences in how the medication is absorbed and in dosage schedules can mean your experience may not be identical, especially during the first few weeks of switching