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It found that in participants with overweight or obesity (body mass index (BMI) 27 kg/m 2 ), once-weekly injections of 5 mg, 10 mg or 15 mg of tirzepatide led to mean weight reductions of 15%, 19.5% and 20.9%, respectively, compared to placebo
The spending increase is driven primarily by higher outpatient costs, an increase of $438 in the first year, likely reflecting monitoring visits for dose titration and managing side effects
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It is generally recommended for people who are obese or have a body mass index (BMI) of 30 or higher
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