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19 BolanosJ

doi: 10.1104/pp.79.4.1044 48 SuX

Kirkeby, A

The reaction was incubated for 10 min at 37 C, the development of GSH-CDNB adduct was measured at 340 nm

It is postulated that glutathione inhibits tyrosinase through three primary mechanisms: direct antioxidant activity, chelation of the copper site within tyrosinase via its thiol group, and disruption of tyrosinases cellular transport to pre-melanosomes