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Users who continue aggravating activities during treatment often see minimal benefit

Methods 15 , 617622 (2018)

However, for advanced experimental models, it can be combined with NAD+ (for mitochondrial redox optimization) or SS-31 (for enhanced mitochondrial membrane protection)

Approximately 2% of the oxygen consumed by the mitochondria is converted into superoxide, making it one of the largest sources of endogenous ROS ( via -oxidation of fatty acid and flavin oxidase reaction and degrading ROS via catalase-mediated breakdown of H 2 O 2 ( Table 1 Formation of major oxidants

It is used exclusively as a research tool compound