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Description

Here, FITC-conjugated agonists act as FRET acceptors when bound to GLP-1Rs labeled with lanthanide (terbium) SNAP-tag probes 42

A key challenge lies in its interaction with drug-metabolizing enzymes, particularly cytochrome P450 enzymes, particularly CYP3A4, which is involved in the metabolism of many drugs [12, 116, 117]