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Using fat, which has more than double the calories of protein and carbohydrates, as a source of energy during exercise not only contributes to weight loss, but also positively affects the body's performance and endurance
This effect is most pronounced during dose escalation and when patients experience gastrointestinal symptoms, with some attenuation of this effect occurring with continued use at stable doses
Abdominal vagal afferent pathways and their distributions of intraganglionic laminar endings in the rat duodenum
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2.5 mg to 15 mg maintenance Mean weight loss (standard dose) Wegovy: ~13.7% at 72 weeks (SURMOUNT-5) Mounjaro: ~20.2% at 72 weeks (SURMOUNT-5) Available in Ireland Wegovy: Yes - private prescription Mounjaro: Yes - private prescription HSE reimbursement Wegovy: Not yet (NCPE review ongoing) Mounjaro: Not yet Access and Cost in Ireland in 2026 Both Wegovy and Mounjaro are available in Ireland on private prescription
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