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Research indicates that upon MC1R binding, MT-1 triggers the cAMP signaling cascade, leading to activation of protein kinase A (PKA) and subsequent upregulation of microphthalmia-associated transcription factor (MITF)
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Figure 1 Although previous studies have demonstrated that GLP-1 has positive effects on attenuating neuropathology, its function and specific actions in CNS diseases have not been reviewed comprehensively
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