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Even more striking, at the 48-week endpoint, the 12 mg retatrutide group achieved a mean weight reduction of 24.2%, translating to an average weight loss of 57.8 pounds (26.2 kg)
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The vagal nerve is likely to play an essential role in the transmission of -synuclein fibrils from the gut to the brain 24
GLP-1 medications work partly by influencing the brain circuits involved in set point regulation, which is why they produce larger and more sustained weight loss than dietary approaches
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