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Every few years a new weight-loss medication comes along that changes the conversation
The biological effects at these doses are subtle enough that you may not notice the inconsistency, but the variable exposure undermines the purpose of a controlled protocol
Only benefit was reduced bloating on refeed days / drinking AOD is one of those peptides to go from 7% to 6%
However, the timeline may be slightly longer because your baseline metabolic rate is lower, meaning the appetite-suppression effect of semaglutide must work harder to create a meaningful calorie deficit
Indeed, the consequences of naturally occurring mutations in GLP1R gene on receptor function and metabolic traits related to T2D and obesity, as well as the responsiveness to current GLP1R-based treatments had not been clearly established
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